Health Capital Helsinki
  • Home
  • Why Helsinki Metropolitan
  • About
  • News
  • Events
  • Opportunities
  • Careers
  • Contact
  • Search
  • Menu Menu
Maija Astikainen / Helsinki Partners
Oct 5, 2023

The Finnish genomics study FinnGen enters its next phase with €52M of new funding

The FinnGen research consortium has successfully collected and generated genomic data from 500,000 individuals in Finland. Now, the project will continue its search for genetic clues to disease progression and explore the biological mechanism of the genetic signals uncovered in the first stages of the project. Since its initiation in 2017, the FinnGen study has developed into one of the world’s leading biobank-based genomic research projects.

FinnGen has now completed the construction of a research resource that integrates genomic information from half a million Finnish biobank participants with decades of national health registry data. In addition to an unparalleled lifelong view on health and disease, a unique aspect of FinnGen is its broad public-private collaboration model. The research consortium, led by the University of Helsinki, includes 15 Finnish academic partners and 13 international pharmaceutical companies.

The agreement covering the next phase of the study secures approximately 52 million euro in new international investment to the Finnish health research ecosystem.

“We are thrilled to enter the next exciting chapter of FinnGen and move from the data resource construction and gene identification phase to the phase of understanding disease mechanisms and disease progression, to enhance drug target prioritisation”, says FinnGen’s Scientific Director, Professor Aarno Palotie from the Institute for Molecular Medicine Finland (FIMM), University of Helsinki.

Identification of novel disease-associated variants is possible with a much smaller number of patients in Finland than elsewhere in the world.

From genetic discoveries to a fundamental understanding of health and disease

FinnGen has earlier demonstrated that the identification of novel disease-associated variants is possible with a much smaller number of patients in Finland, than elsewhere in the world. Due to its unique geographic position and linguistic isolation, the modern Finnish population, despite being broadly similar to Europeans genetically, has an unusual and large set of genetic variants rarely found elsewhere in the world.

During the past few years, the FinnGen resource has been successfully deployed in genetic discovery activities and the research community has identified more than a thousand medically relevant genetic variants, including novel risk-causing and protective variants for both common and rare diseases.

The future activities will address a key challenge that has hindered the transition of genetic discoveries into novel medicines and diagnostics: understanding the biological processes that are involved in disease initiation, progression, severity and therapeutic responses.

The future activities will address understanding the biological processes that are involved in disease progression.

During the next four years, FinnGen will engage in studies that are expected to enhance our understanding of the longitudinal aspects of health and disease, with the hope of discoveries that could lead to ways to influence disease progression. For this, the consortium will get access to historical biological samples and additional health care data types, including extensive clinical laboratory values and information about hospital-based medications.

The new molecular and clinical data will be combined with the existing data resource to allow further scientific breakthroughs.

“Now the aim is to leverage new findings that, in combination with other international studies, can move the field forward and provide tools for improving disease prevention, treatment and finally personalised health care”, Aarno Palotie concludes.

Full press release

About FinnGen

The FinnGen study, launched in the autumn of 2017, is a broad academic-industrial collaboration between the Finnish biobanks and their respective universities and wellbeing service counties, the Finnish Institute of Health and Welfare (THL), the Finnish Red Cross Blood Service, the Finnish Biobank Cooperative – FINBB and thirteen international pharmaceutical companies. The current phase of the study is being supported by AbbVie, AstraZeneca, Biogen, Boehringer Ingelheim, Bristol Myers Squibb, Genentech, a member of the Roche Group, GSK, Janssen Biotech, Inc. (part of the Janssen Pharmaceutical Companies of Johnson & Johnson), Maze Therapeutics, MSD (the trade name of Merck Sharp & Dohme LLC), Novartis, Pfizer and Sanofi. These companies also funded phases 1 and 2, along with Business Finland. The academic organisation responsible for the study is the Institute for Molecular Medicine Finland FIMM at the University of Helsinki.

More news

Health Capital Helsinki

Event speakers at the stage of the Radical Health Festival Helsinki in 2024Pekka Hannila / Helsinki Expo and Convention Centre

Helsinki to host the 3rd edition of the Radical Health Festival Helsinki in 2026

https://ecshuqpetk9.exactdn.com/wp-content/uploads/2025/01/2M1A2739-1.jpg?strip=all&lossy=1&quality=55&ssl=1 1365 2048 Saana Lehtinen https://ecshuqpetk9.exactdn.com/wp-content/uploads/2020/02/hch_logo_horizontal_black-300x165-1.png Saana Lehtinen2025-01-27 11:21:122025-01-27 11:40:35Helsinki to host the 3rd edition of the Radical Health Festival Helsinki in 2026
A man with headphones and mobile phone in front of Oodi Central Library in HelsinkiAleksi Poutanen / Helsinki Partners

Free training materials: Cybersecurity for health startups and growth companies

Jan 7, 2025
https://ecshuqpetk9.exactdn.com/wp-content/uploads/2023/06/Man_at_Oodi_AleksiPoutanen.jpg?strip=all&lossy=1&quality=55&ssl=1 827 1240 Saana Lehtinen https://ecshuqpetk9.exactdn.com/wp-content/uploads/2020/02/hch_logo_horizontal_black-300x165-1.png Saana Lehtinen2025-01-07 13:17:452025-01-07 15:29:08Free training materials: Cybersecurity for health startups and growth companies
EsaDres team: Dr Marta Putrinš, Prof Karin Kogermann and Kairi Lorenz

EsaDres redefines wound care with tailored solutions

https://ecshuqpetk9.exactdn.com/wp-content/uploads/2024/10/EsaDres-team-2024.jpg?strip=all&lossy=1&quality=55&ssl=1 1016 2200 Saana Lehtinen https://ecshuqpetk9.exactdn.com/wp-content/uploads/2020/02/hch_logo_horizontal_black-300x165-1.png Saana Lehtinen2024-12-10 08:03:222024-12-12 14:13:44EsaDres redefines wound care with tailored solutions
All news

Health Capital Helsinki

Business Helsinki
Kansakoulukatu 3
00100 Helsinki
FINLAND

Privacy notice

Newsletter

Subscribe

Follow us

  • x
  • linkedin
Health Capital Helsinki
Scroll to top

We use cookies to give you the best experience on our website.

Find out more and set your preferences .

Powered by  GDPR Cookie Compliance
How we use cookies

We may request cookies to be set on your device. We use cookies to let us know when you visit our websites, how you interact with us, to enrich your user experience, and to customize your relationship with our website.

Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may impact your experience on our websites and the services we are able to offer.

Essential website cookies

These cookies are strictly necessary to provide you with services available through our website and to use some of its features.

Because these cookies are necessary to deliver the website as intended, refusing them will have impact how our site functions. You can always block or delete cookies by changing your browser settings and force blocking all cookies on this website. But this will prompt you to accept or refuse cookies every time you revisit our site.

We fully respect if you want to refuse cookies but to avoid asking you again and again kindly allow us to store a cookie for that. You are free to opt out any time or opt in for other cookies to get a better experience. If you refuse cookies we will remove all set cookies in our domain.

If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again.

Third party cookies

This website uses Twitter's and LinkedIn's cookies to help us improve our content and reach.

Please enable essential website cookies first so that we can save your preferences!

Privacy notice

You can read about how we use your data on our Privacy notice page.

Privacy notice